Atlético v Man United
Pressure builds on Michael Carrick as 10-man Man United slip to 2-0 defeat to Atlético Madrid
Manchester United's winless run extended to a fifth match as Michael Carrick's side made a nightmare start and lost Leny Yoro to a red card in Tuesday's 2-0 Champions League defeat at Atlético Madrid.
The feel-good factor that came with the Red Devils' surprising return to European football's top table under their former midfielder has been replaced by growing questions over the head coach's future.
United were booed after conceding a stoppage-time leveller at home to struggling Tottenham on Saturday and three days later it was a slow start that proved costly as Pablo Barrios scored after just 50 seconds.
Johnny Cardoso saw a goal ruled out for handball and Atleti twice hit the woodwork as Diego Simeone's side attempted to see off a spirited response from Carrick's men.
Bruno Fernandes crashed an effort off the crossbar as United pushed for a second-half leveller, only to be reduced to 10 men as Yoro was adjudged to have brought down Jonathan David as last man.
Substitute Ademola Lookman quickly added a second to end the contest, with this loss increasing the spotlight on Carrick ahead of travelling to rivals Leeds with their lowest points after six league games since 1986.
The United boss made five changes from the Spurs draw, with Ayden Heaven deployed at left-back in place of the injured Luke Shaw in a makeshift backline punished within a minute of kick-off.
Álex Baena all too easily ran behind dozing Diogo Dalot to meet a clipped ball with patience and made a smart pass over to Barrios, whose driven shot was sent trickling over the line by Heaven.
United could have folded but instead made an encouraging response. Bryan Mbeumo saw a shot deflect narrowly wide after some nice footwork and later followed a burst with a strike that tested Jan Oblak.
Carlos Baleba, making his first United start, won the ball in that move and soon saw a header saved by Atleti's goalkeeper, but United rode their luck as the half came to a close.
Alejandro Grimaldo hit the woodwork with a curling free-kick and Cardoso sparked celebrations on the stroke of half-time.
The midfielder scored with a fierce strike from the edge of the box, but Heaven had appealed for handball against Marcos Llorente in the build-up and referee Glenn Nyberg agreed after being sent to the monitor.
Atleti continued to threaten when the second half got under way, with a ball met by an equally impressive Julián Álvarez volley off the near post in the 54th minute.
There was a sharp intake of breath when United skipper Fernandes directed just wide having stretched to meet a diagonal Youri Tielemans ball three minutes later, but Atleti continued to push through lively Baena.
Fernandes saw a shot deflect behind and went agonisingly close in the 70th minute to finally eking out an equaliser when hitting a bending first-time effort that rattled the crossbar.
But a promising period for United ended when VAR Pol van Boekel sent Nyberg to the monitor.
David had gone down under pressure from Yoro when attempting to run through and the Swedish referee eventually brandished a 74th-minute red card.
Atleti made the most of their man advantage five minutes later. David forced a save from Senne Lammens and fellow substitute Lookman turned into the empty net.
That goal took the wind out of United but there was a late push, meaning Oblak had to be alert in stoppage time to prevent Matheus Cunha from scoring a consolation in front of a largely emptied away section.