Esteghlal emerged from a tough Group C on the final day of matches while Xavi's Al Sadd couldn't get enough help to advance.
Al Nassr booked their ticket with a win over Al Sadd, while three sides have a shot in Group C. Here's a look ahead of the final day of matches.
It has been almost 30 years since a team from Iran has won a club title in Asia. Can Persepolis or Esteghlal finally break through?
Tournament debutants Istiklol picked up their first-ever win in the AFC Champs League moving them into a share of the top spot in Group A.
Ahead of the start of West Zone action in AFC Champions League 2021, we look at the five major talkings points from Asia's premier club competition.
Former Thailand and Cameroon head coach Winfried Schafer, of Germany, has been appointed as the new manager of Iranian giants Esteghlal FC.