Henderson returned a positive test for coronavirus more than three weeks ago but despite since testing negative, Solskjaer said the 24-year-old has still not felt ready to return to training.
"Dean was positive early on and then he's negative in his testing but has not felt as energised or sharp as he has done," Solskjaer said after the 4-0 win over Rafael Benitez's side.
"He feels fatigued and the after effects, you see so many effects of this virus, he's still got a few days to rest and then we'll check up on him."
"Anthony has had a bad spell with injury," Solskjaer added. "He's been training well with us and players out for a while, they need more sharpness, need more work.
"He felt good after, no side effects and hopefully it'll be the same when he comes back into training again."
"The medical with Raphael has to be done," Solskjaer said. "He's isolating at the moment. He had to wait for visas and unfortunately that took a few more days than expected but we've got to follow the protocols and the rules."