Winthrop (18-11, 12-6) came into the regular-season finale a game back of UNC Asheville, where the Eagles lost on Thursday, but fell behind by 19 points with nine minutes remaining. The Buccaneers made 10 of 12 free throws in the final 41 seconds to hold off the Eagles.
Xavier Cooks caught an inbounds pass at the center of the 3-point arc with 1.2 seconds left but his turnaround 3-point try missed.
Keeling became the fifth Big South sophomore to reach 1,000 career points. Cortez Mitchell added 10.
Charleston Southern (14-15, 9-9) had not won in Winthrop Coliseum since Jan. 24, 2002, a string of 16 losses.
Nwora, Williams power Louisville easily past Southern 104-54
Jordan Nwora scored a career-high 20 points as Louisville easily dominated Southern 104-54 Tuesday night.
Weir has career night, leads Purdue Fort Wayne to 111-65 win
Matt Weir came off the bench to score 22 points with eight assists and five rebounds, all career highs, as Purdue Fort Wayne thrashed Division III Manchester 111-65 on Tuesday night.
No. 22 LSU pushes past Memphis 85-76
Freshman Emmitt Williams is one of five players to finish in double figures against Memphis.