Brandon Cyrus scored 12 and Austin Grandstaff had 11 for the Blue Demons (6-4), who won their fifth straight while keeping the Bulldogs (0-9) winless. DePaul has its longest streak since winning seven straight in the 2012-13 season.
DePaul opened the game with a 25-5 run and led by 29 before going into halftime up 48-22. The Blue Demons kept the lead above 20 except once when the Bulldogs made it 53-34 early in the period.
DePaul had its largest lead at 76-45 on McCallum's 3-pointer with 5:32 to go.
Simmons, Duffy help North Texas beat Hawaii 68-51
Jahmiah Simmons and Jorden Duffy scored 13 points apiece to help North Texas beat Hawaii 68-51 on Sunday night.
Carter, Mean help Seattle beat Bryant 82-59
Myles Carter had 25 points and 12 rebounds and Morgan Means scored 21 points to help Seattle beat Bryant 82-59 on Sunday night.
Second-half rally helps Vanderbilt hold off USC, 82-78
Darius Garland had 19 points, Simisola Shittu added 14 points and 15 rebounds and Vanderbilt beat USC 82-78 on Sunday night.