Glory stars no guarantee to face Adelaide

Play it safe or go full bore with Diego Castro and Matthew Spiranovic?

That's the question facing Perth Glory coach Tony Popovic ahead of Wednesday night's A-League clash with Adelaide United at HBF Park.

Popovic has heavily rotated his squad during the busy January period, making a whopping 16 changes to his starting line-up over the past three matches.

The veteran coach has been particularly cautious with Castro and Spiranovic following the duo's injury struggles over the past year.

Spiranovic missed a year of action with a hip injury before suffering a hamstring setback earlier this season.

Castro has battled two separate hamstring injuries this campaign, restricting him to just three starts and four cameos off the bench.

The duo started in last Saturday's 0-0 draw with Melbourne City at AAMI Park.

Castro was taken off in the dying minutes, while Spiranovic played out the match.

But whether Popovic will be willing to risk them just four days later against Adelaide remains to be seen.

One option is for Popovic to rest the duo against Adelaide - or give them a short burst from the bench - in order to have them fresh and firing for Sunday's home clash with Newcastle.

Popovic said he was yet to decide on his squad for the clash with Adelaide, but said players' histories would be taken into account.

"Certain players who are coming off injuries are not at the same level as someone who has played every game," Popovic said.

"Some players look as though they need a bit of a rest. No player will tell you that, because they all want to play, and that's what we want.

"That's something that's been a positive from the group - they want to be involved and they want to play every minute of every game."

Adelaide will be without suspended defender Michael Jakobsen after he picked up his fifth yellow card of the season in last week's 2-1 win over Western Sydney.

Glory, who have lost just once in 14 games this season, are three points clear on top of the table.

Sixth-placed Adelaide are 11 points further adrift, and Popovic has put his team on guard for star United midfielder Isaias Sanchez.

"He's an outstanding player and he'll always have his moments in a game - like Diego would for us," Popovic said.

"Our job is to try to keep him very busy defending (so there's) less time for him to create opportunities for his teammates."

STATS THAT MATTER

*Glory striker Andy Keogh has scored six goals in his past seven A-League games against Adelaide.

*Adelaide are unbeaten in their past 13 A-League games played on a weekday, winning eight and drawing five. They conceded just one first-half goal during that stretch.

*Perth Glory (56 per cent) have the highest shooting accuracy of any team this season, 13 per cent higher than Adelaide.