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Juventus were denied the chance of winning Serie A for a record eighth time in a row on Saturday, following a shock 2-1 defeat at SPAL.
Claudio Ranieri's AS Roma side suffered a blow to their top-four hopes in Serie A as they went down to a surprise 2-1 defeat at struggling SPAL.
Inter Milan bounced back to beat SPAL 2-0 in Serie A on Sunday and stay on course for a Champions League spot next season.
Sampdoria's in-form veteran forward Fabio Quagliarella scored two early goals to lead his side to a 2-1 win at SPAL.
A controversial decision from a Video Assistant Referee (VAR) review proved crucial as Fiorentina overcame SPAL 4-1 in Serie A on Sunday at the Stad
Torino coach Walter Mazzarri was left fuming with the refereeing after Nicolas N'Koulou was sent off during his side's 0-0 draw at SPAL.
AC Milan ended a four-match goal drought and striker Gonzalo Higuain was on target for the first time in two months as they beat SPAL on Saturday.